Apply to affected areas daily or as directed by a doctor. Use before going to bed for 4 weeks. Apply 4 doses on dry or towel-dried scalp, section by section (1 dose= 1 pipette until the mark). Leave on overnight and do not rinse. In case of contact with eyes, rinse them immediately and thoroughly. For best anti-dandruff efficacy, use Scalp Renewal Exfoliating Antidandruff Scalp Scrub before applying this serum.